🌍 Global Infectious Diseases & One Health Conference
👩🔬 Presenter: Jianghong Wu
🏫
Affiliation: Shenzhen Technology University, China
🎤
Presentation Type: Speaker Presentation
🦠 Advancing Rapid Detection of Influenza A
Influenza
A viruses circulate globally each year and pose a significant threat to public
health due to their high transmissibility. Rapid and accurate detection
is essential for early intervention and outbreak control.
Traditional
diagnostic methods such as Reverse Transcription Polymerase Chain Reaction
(RT-PCR) provide excellent analytical performance. However, their
dependence on complex instruments and trained professionals limits their
use in rapid, on-site testing.
To
overcome these challenges, researchers have developed a smartphone-assisted
electrochemical biosensor platform designed for sensitive, portable, and
rapid detection of Influenza A.
📱 Smartphone-Based Biosensor Technology
This
innovative sensing platform integrates:
🔬 Screen-printed electrodes (SPEs)
🧲
Magnetic beads with immobilized DNA probes
📱
Smartphone-based signal processing and results display
The system
captures and isolates viral nucleic acids while enabling real-time
electrochemical detection using portable devices.
⚡
Signal Amplification Strategies
To enhance
detection sensitivity, methylene blue (MB) is used to intercalate into
double-stranded nucleic acid structures and generate measurable electrochemical
signals.
Additional
amplification strategies include:
🔹 Adding [Fe(CN)₆]³⁻/⁴⁻ electrolyte, increasing
signal strength 3 times
🔹
Using Prussian Blue Analogues (PBA) mediator layers, increasing signal
strength up to 50 times
The
electrochemical responses are recorded through a smartphone-based
potentiostat, creating a compact and accessible diagnostic system.
📊 High Sensitivity and Rapid Testing
The
developed platform demonstrates:
📈 Linear detection range: 0.5 aM – 100 nM
🔍
Detection limit: 2.01 aM
⏱
Test time: Less than 1 hour
This
sensitivity is comparable to RT-PCR, yet the method eliminates
nucleic acid amplification, simplifying the entire diagnostic process.
🚀 Future of Point-of-Care Diagnostics
By
combining magnetic bead-assisted nucleic acid capture with portable
electrochemical detection, this platform offers a promising solution for next-generation
point-of-care testing for infectious diseases.
👩🔬 Biography
Jianghong
Wu is an Associate Professor at Shenzhen Technology University, China,
specializing in rapid detection technologies for infectious diseases.
She
obtained her PhD in Materials Science and Engineering from Donghua
University (2013) and later worked as a postdoctoral researcher at the
State Key Laboratory of Chemo/Biosensing and Chemometrics at Hunan University.
Her research focuses on electrochemical biosensors for rapid detection, early diagnosis, and health monitoring, contributing to innovative diagnostic technologies for infectious disease control.
🌍 Conference Details
📅 Dates: September 21–23
📍
Venue: London, United Kingdom & Online
🔗 Event Website: https://infection.miconferences.com/
📝
Registration: https://infection.miconferences.com/register
📧 Email: infection@mathewsconference.com
📞
Phone: +1 (312) 462-4448
💬
WhatsApp: +1 (424) 377 0967
#InfectiousDiseases
#InfluenzaResearch #Biosensors #PointOfCareTesting #MedicalTechnology
#GlobalHealth #Diagnostics #MedicalConference #OneHealth #LondonConference
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